Endocrine Abstracts

Introduction: Li-Fraumeni syndrome is a rare disorder that greatly increases the risk of developing several types of cancer, particularly in children and young adults. It is a hereditary disease with high penetrance autosomal dominant transmission that is due, in 70% of the cases, to germline mutations in the gene TP53. The most common cancers associated with this disorder are brain tumors, sarcomas, breast cancer and adrenocortical tumors.Methods: We de...

Introduction: Hypercalcemia of malignancy usually appears in patients with osteolytic metastasis and in those patients with humoral hypercalcemia due to secretion of PTHrp by the tumor. Hypercalcemia due to calcitriol production by the tumor is uncommon (<1% of cases of hypercalcemia of malignancy). It is the cause of virtually all cases of hypercalcemia in patients with Hodgkin’s lymphoma and approximately one third of cases in non-Hodgkin’s lymphoma. It has als...

Introduction: The differential diagnosis of cystic cervical masses includes thyroid cyst, thymic cyst, thyroglossal duct cyst, branchial cleft cyst, bronchogenic cyst, lymphangioma and parathyroid cyst (PC). PC is one of the less common causes of the cervical masses.Methods: We report the case of a 37-year-old man admitted to the hospital with a neck mass of 48 mm.Results: Our patient presented with neck pain and an hipoechogenic n...

Introduction: Adrenocortical carcinoma (ACC) is a very rare neoplasm with an incidence of about one case per million population. It is an agressive tumor (overall 5-year survival 16–38%) and complete resection is the only curative treatment.Description of methods: We report four cases of ACC. The clinical and biochemical features at diagnosis along with clinical course of the disease are discussed.Results: Four patients (three...

Objectives: The prevalence of diabetic patients admitted in hospitals close to 20% in some series. Our goal is to determine the prevalence of diabetic patients assessed by interclinical calls from different medical and surgical specialties that have been entered during 2015 in our Hospital, in order to describe the characteristics that these diabetic patients.Material and methods: We present 116 patients evaluated by interclinical consultation request fo...

Introduction: Transsphenoidal surgery is the preferred approach in patients with pituitary tumours. Transsphenoidal resection of pituitary tumors may account for as much as 20% of all intracranial operations performed for primary brain tumors. Meningitis is a rare complication accounting for less than 2% of procedures.Methods: We report the case of an elderly patient with a sellar mass who was admitted to the hospital with a central nerve system infectio...

Introduction: Amyloidosis is a rare systemic disease of unknown etiology characterized by the extracellular deposition of proteinaceous (amyloid) material in different organs of the body. About 40-50% are of secondary cause (Amyloidosis AA) Amyloid goiter is a rare condition, usually associated with the secondary form.Case: We reported a 41-year-old male with a history of non-steroidal anti-inflammatories, high blood pressure and smoking habit. Maintains...

Introduction: Persistent hyperinsulinemic hypoglycemia may be caused either by a solitary tumor of the pancreas secreting excessive amount of insulin, known as insulinoma or, rarely, by nesidioblastosis. Nesidioblastosis is a rare cause of persistent hyperinsulinemic hypoglycemia in adults.Methods: We describe the case of a 25-year-old male patient who was referred to our clinic for repeted hypoglycemia episodes.Results: Our patien...

Introduction: Evaluation of postmenopausal hyperandrogenism may be a challenge for physicians as it is necessary to exclude the presence of the relatively rare but potentially life-threatening underlying tumorous causes. We report the case of a postmenopausal woman who presented with clinical and biochemical hyperandrogenism.Case Report: We present the case of a 65 year-old woman being followed at our clinic because of mild hypothyroidism. At inspection ...

Introducción: Thyroid nodule is a very frequent pathology that affects 4-8% of population. Fine-needle aspiration (FNA) guided by ultrasound (US) is considered the gold standard test in diagnostic evaluation of thyroid nodules. This technique is being assumed more and more frequently by endocrinologists.Description of Methods: We conducted a retrospective study that included all thyroid US-guided FNA performed in 2014. We considered the following va...